Lipid Profile as a Nutritional Status Marker in Tuberculosis
Published: December 1, 2020 | DOI: https://doi.org/10.7860/JCDR/2020/45522.14266
Vaishnavi Sandip Salunkhe, Vinayak Wamanrao Patil, Pooja Rai
1. Assistant Professor, Department of Biochemistry, LTMMC and GH, Sion Hospital, Mumbai, Maharashtra, India.
2. Professor and Head, Department of Biochemistry, Vedantaa Institute of Medical Sciences, Dahanu, Mumbai, Maharashtra, India.
3. Associate Professor, Department of Biochemistry, LTMMC and GH, Sion Hospital, Mumbai, Maharashtra, India.
Correspondence
Vaishnavi Sandip Salunkhe,
Room No. 305A, Department of Biochemistry, 3rd Floor, College Building,
LTMMC and GH, Sion Hospital, Sion, Mumbai-400022, Maharashtra, India.
E-mail: vaishnavisalunkhe@gmail.com
Introduction: Tuberculosis (TB) is a global health problem. India has the highest cases in the world and accounts for nearly one fifth of global cases. TB is a chronic disease and in long term leads to malnutrition. Lipids are important constituents in the body that determine the nutritional status and immune function.
Aim: To study lipid profile as a nutritional status marker in pulmonary TB.
Materials and Methods: Fifty patients of pulmonary TB and fifty healthy subjects in age group of 18-60 years were included for study. The lipid profile was analysed to assess the nutritional status of the patients. Unpaired t-test was used to study the significance of study parameters in cases and controls group. The p-value of <0.05 was considered to be statistically significant.
Results: Out of 100 subjects 63% were males 37% were females. Significant decreased levels of total cholesterol, Triglycerides, High Density Lipoprotein-Cholesterol (HDL), Very Low Density Lipoprotein-Cholesterol (VLDL), Low Density LipoproteinCholesterol (LDL) were seen in cases as compared to controls.
Conclusion: In this study, it was observed that lipid profile could play a significant role as a biochemical marker of nutritional status in pulmonary TB patients. Thus, knowledge of these levels can help in providing a proper balanced diet to these patients which can ultimately help in better quality treatment.
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